Article
Genetics of apolipoprotein H (beta2-glycoprotein I) and anionic phospholipid binding.
Lupus - 1 Jan 1998
Kamboh M I, Mehdi H
Abstract excerpt
Apolipoprotein H (apoH; also known as beta2-glycoprotein I), is an essential cofactor for the binding of certain antiphospholipid antibodies (APA) to anionic phospholipid. The gene coding for apoH is polymorphic, with the occurrence of several common alleles in the general population. This geneti...
Topics
- Alleles
- Amino Acid Substitution
- Animals
- Anions
- Antiphospholipid Syndrome
- Autoimmune Diseases
- COS Cells
- Cardiolipins
- Codon
- Genotype
- Glycoproteins
- Humans
- Phosphatidylserines
- Phospholipids
- Point Mutation
- Polymorphism, Genetic
- Protein Binding
- Protein Structure, Tertiary