Heterogeneity of the apolipoprotein H*3 allele and its role in affecting the binding of apolipoprotein H (beta 2-glycoprotein I) to anionic phospholipids.

doi:10.1007/BF00208960

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Article

Heterogeneity of the apolipoprotein H*3 allele and its role in affecting the binding of apolipoprotein H (beta 2-glycoprotein I) to anionic phospholipids.

Human genetics - 1 Apr 1995

Kamboh M I, Wagenknecht D R, McIntyre J A

Abstract excerpt

Apolipoprotein H (apoH, protein; APOH, gene) has been implicated as a necessary cofactor for the binding of certain autoimmune antiphospholipid antibodies to anionic phospholipids. APOH exhibits genetically determined structural polymorphism with the occurrence of four alleles. Recently three IgG1k monoclonal antibodies (mAb) to human apoH, designated 3G9, 1B4, and 3D11, have been produced. The mAb 3D11 does not...

Topics

Adult
Alleles
Anions
Antibodies, Monoclonal
Apolipoproteins
Binding, Competitive
Child, Preschool
Female
Glycoproteins
Humans
Immunoblotting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin G

Isoelectric Focusing

Male

Phosphatidylserines

Racial Groups

beta 2-Glycoprotein I

Source

Open in PubMed

Identifiers

PMID: 7705832
DOI: 10.1007/BF00208960

Genes

APOH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7705832-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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