Article
Molecular basis of the apolipoprotein H (beta 2-glycoprotein I) protein polymorphism.
Human genetics - 1 Jul 1997
Sanghera D K, Kristensen T, Hamman R F, Kamboh M I
Abstract excerpt
Apolipoprotein H (apoH, protein; APOH, gene) is considered to be an essential cofactor for the binding of certain antiphospholipid autoantibodies to anionic phospholipids. APOH exhibits a genetically determined structural polymorphism due to the presence of three common alleles (APOH*1, APOH*2 and APOH*3) detectable by isoelectric focusing (IEF) and immunoblotting. The APOH*3 allele can be further characterized...
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