Article
No association between mannose-binding lectin alleles and susceptibility to chronic hepatitis B virus infection in German patients.
Experimental and clinical immunogenetics - 1 Jan 1998
Höhler T, Wünschel M, Gerken G, Schneider P M, Meyer zum Büschenfelde K H, Rittner C
Abstract excerpt
Variants of the mannose-binding lectin (MBL) have been shown to be associated with low serum concentrations of the protein and to predispose to bacterial, fungal and viral infections. A recent small study on 33 Caucasian patients had suggested that a mutation at codon 52 of the MBL gene is associated with chronic hepatitis B virus (HBV) infection. Exon 1 of the MBL gene was amplified by PCR in 61 patients with...
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