Article
No association between mannose-binding lectin alleles and susceptibility to chronic hepatitis B virus infection in German patients.
Experimental and clinical immunogenetics - 1 Jan 1998
Höhler T, Wünschel M, Gerken G, Schneider P M, Meyer zum Büschenfelde K H, Rittner C
Abstract excerpt
Variants of the mannose-binding lectin (MBL) have been shown to be associated with low serum concentrations of the protein and to predispose to bacterial, fungal and viral infections. A recent small study on 33 Caucasian patients had suggested that a mutation at codon 52 of the MBL gene is associ...
Topics
- Acute Disease
- Adult
- Alleles
- Carrier Proteins
- Collectins
- DNA
- Electrophoresis, Agar Gel
- Genetic Predisposition to Disease
- Hepatitis B
- Hepatitis B, Chronic
- Humans
- Mutation
- Polymerase Chain Reaction
- Prospective Studies