Article
Association of mannose-binding lectin polymorphisms and HBV outcome in a South Indian population.
International journal of immunogenetics - 1 Jun 2010
Fletcher G J, Gnanamony M, Samuel P, Ismail A M, Kannangai R, Daniel D, Eapen C E, Abraham P
Abstract excerpt
Mannose binding lectin (MBL) is an important innate immune system pattern recognition molecule. The MBL gene polymorphisms are reported to play a crucial role in outcome of hepatitis B virus (HBV) infection. In this study, we ascertained the association of MBL genotypes with HBV outcome in a South Indian population. The MBL gene polymorphisms at codons 52, 54 and 57 of exon I, and promoter polymorphisms at -221...
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