Article
Mapping of the sites involved in ligand association and dissociation at the extracellular domain of the kinase insert domain-containing receptor for vascular endothelial growth factor.
The Journal of biological chemistry - 20 Nov 1998
Shinkai A, Ito M, Anazawa H, Yamaguchi S, Shitara K, Shibuya M
Abstract excerpt
The kinase insert domain-containing receptor (KDR) for vascular endothelial growth factor (VEGF) has been shown to be involved in vasculogenesis and angiogenesis. This receptor is characterized by seven immunoglobulin (Ig)-like domains within its extracellular region. To identify the domains invo...
Topics
- Binding Sites
- Biosensing Techniques
- Endothelial Growth Factors
- Humans
- Lymphokines
- Mutation
- Peptide Fragments
- Protein Binding
- Receptor Protein-Tyrosine Kinases
- Receptors, Antigen, B-Cell
- Receptors, Growth Factor