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Article

Adenovirus 5 E1A-mediated tumor suppression associated with E1A-mediated apoptosis in vivo.

Oncogene - 29 Oct 1998

Deng J, Xia W, Hung M C

Abstract excerpt

Disruption of apoptotic pathways is a major factor in the multistep process of tumorigenesis, whereas induction of apoptosis can be important for tumor suppression and cancer therapy. The adenovirus type 5 E1A gene provides a useful tool to study the function of tumor suppression and apoptosis. E1A has been shown to induce apoptosis in different systems in vitro. However, this activity has not been well...

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Identifiers

PMID: 9811448
DOI: 10.1038/sj.onc.1202148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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