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Article

Association of the COL1A1 gene polymorphisms in Mexican postmenopausal women with fracture or with low bone mineral density at the hip.

Aging clinical and experimental research - 1 Jun 2016

Falcón-Ramírez Edith, Hidalgo-Bravo Alberto, Barredo-Prieto Blanca Alicia, Pineda-Gómez Ernesto, Valdés-Flores Margarita

Abstract excerpt

BACKGROUND AND AIMS: Osteoporosis leads to high fracture risk and evidence suggests that genetic factors play an important role in this disease. The aim was to evaluate the association of two polymorphisms (-1997G/T, +1245G/T) in the collagen type1 alpha 1 gene (COL1A1) with fracture or with low bone mineral density (BMD) at the hip in postmenopausal Mexican women. METHODS: BMD was determined by bone densitometry...

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PMID: 26423565
DOI: 10.1007/s40520-015-0449-6

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