Article
The homozygote of HLA-DRB1*0901, not its heterozygote, is associated with rheumatoid arthritis in Japanese.
Scandinavian journal of rheumatology - 1 Jan 1998
Wakitani S, Imoto K, Murata N, Toda Y, Ogawa R, Ochi T
Abstract excerpt
To assess the association between HLA-DRB1*0901 and Japanese rheumatoid arthritis (RA) patients, we analyzed the frequency of HLA-DRB1*0901 in 852 Japanese RA patients. We found that the homozygote of DRB1*0901 was associated with Japanese RA patients, while the heterozygote of DRB1*0901 was not....
Topics
- Alleles
- Arthritis, Rheumatoid
- DNA
- Gene Dosage
- Gene Frequency
- Genetic Predisposition to Disease
- HLA-DR Antigens
- HLA-DRB1 Chains
- Heterozygote
- Homozygote
- Humans
- Japan