Article
Haplotype distribution of class II MHC genes in Mexican patients with systemic lupus erythematosus.
Scandinavian journal of rheumatology - 1 Jan 1998
Bekker-Mendez C, Yamamoto-Furusho J K, Vargas-Alarcón G, Ize-Ludlow D, Alcocer-Varela J, Granados J
Abstract excerpt
The objective of this project was to determine the association of the DQA1*0501 allele in the susceptibility to develop systemic lupus erythematosus (SLE) in Mexicans. Frequencies of generic MHC Class II genes (HLA-DR, DQA and DQB1) were determined by DNA typing in 58 Mexican mestizo SLE patients...
Topics
- DNA
- Gene Frequency
- Genes, MHC Class II
- Genetic Predisposition to Disease
- Genetics, Population
- HLA-DQ Antigens
- Haplotypes
- Humans
- Indians, North American
- Linkage Disequilibrium
- Lupus Erythematosus, Systemic
- Mexico
- Phenotype
- White People