Article
Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus.
Rheumatology (Oxford, England) - 1 Mar 2005
Gambelunghe G, Gerli R, Bocci E Bartoloni, Del Sindaco P, Ghaderi M, Sanjeevi C B, Bistoni O, Bini V, Falorni A
Abstract excerpt
OBJECTIVE: To evaluate the contribution of the MHC class I chain-related A (MICA) gene polymorphism to the genetic risk of systemic lupus erythematosus (SLE). METHODS: HLA-DRB1-DQA1-DQB1 genotyping, MICA exon 5 microsatellite genotyping and HLA-B8 genotyping were performed in 48 Italian SLE patients and in 158 healthy control subjects. RESULTS: Of HLA class II haplotypes, only DRB1*03-DQA1*0501-DQB1*0201...
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