Article
Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates.
Development (Cambridge, England) - 1 Dec 1998
Nilsson L, Li X, Tiensuu T, Auty R, Greenwald I, Tuck S
Abstract excerpt
Induction of vulval fates in the C. elegans hermaphrodite is mediated by a signal transduction pathway involving Ras and MAP kinase. Previous genetic analysis has suggested that two potential targets of this pathway in the vulva precursor cells are two novel proteins, LIN-25 and SUR-2. In this re...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- DNA-Binding Proteins
- Disorders of Sex Development
- Embryonic Induction
- Female
- Fluorescent Antibody Technique, Indirect
- Gene Expression Regulation, Developmental
- Genotype
- Helminth Proteins
- Homozygote
- Hot Temperature
- Mosaicism