Article
Identification of functional human splenic memory B cells by expression of CD148 and CD27.
The Journal of experimental medicine - 2 Nov 1998
Tangye S G, Liu Y J, Aversa G, Phillips J H, de Vries J E
Abstract excerpt
Memory B cells isolated from human tonsils are characterized by an activated cell surface phenotype, localization to mucosal epithelium, expression of somatically mutated immunoglobulin (Ig) variable (V) region genes, and a preferential differentiation into plasma cells in vitro. In spleens of both humans and rodents, a subset of memory B cells is believed to reside in the marginal zone of the white pulp. Similar...
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