Variability in the serotonin transporter gene and increased risk for major depression with melancholia.

doi:10.1007/s004390050823

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Article

Variability in the serotonin transporter gene and increased risk for major depression with melancholia.

Human genetics - 1 Sept 1998

Gutiérrez B, Pintor L, Gastó C, Rosa A, Bertranpetit J, Vieta E, Fañanás L

Abstract excerpt

The serotonin transporter (SERT) gene is a particularly interesting candidate for genetic involvement in affective disorders owing to its role in both the regulation of serotonergic neurotransmission and the mechanism of action of many antidepressant drugs. In this study, variability in the SERT...

Topics

Carrier Proteins
Chromosomes, Human, Pair 17
Depressive Disorder
Female
Genotype
Humans
Male
Membrane Glycoproteins
Membrane Transport Proteins
Middle Aged
Minisatellite Repeats
Nerve Tissue Proteins
Polymorphism, Genetic
Risk Factors
Serotonin Plasma Membrane Transport Proteins
Spain

Source

Open in PubMed

Identifiers

PMID: 9799087
DOI: 10.1007/s004390050823

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9799087-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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