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Article

Variability in the serotonin transporter gene and increased risk for major depression with melancholia.

Human genetics - 1 Sept 1998

Gutiérrez B, Pintor L, Gastó C, Rosa A, Bertranpetit J, Vieta E, Fañanás L

Abstract excerpt

The serotonin transporter (SERT) gene is a particularly interesting candidate for genetic involvement in affective disorders owing to its role in both the regulation of serotonergic neurotransmission and the mechanism of action of many antidepressant drugs. In this study, variability in the SERT gene was analyzed for the first time in a sample of patients with major depression with melancholia (MDDM) in the...

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PMID: 9799087
DOI: 10.1007/s004390050823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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