Article
Analysis of the three-dimensional antigenic structure of giant ragweed allergen, Amb t 5.
Molecular immunology - 1 Jun 1998
Rafnar T, Brummet M E, Bassolino-Klimas D, Metzler W J, Marsh D G
Abstract excerpt
The ragweed allergens Amb t 5 and Amb a 5 are among the smallest inhaled protein allergens known, containing a single, immunodominant T-cell epitope. In this study we analyzed the B-cell epitope structure of Amb t 5. The three-dimensional structures of Amb t 5 and Amb a 5 have been determined by...
Topics
- Allergens
- Amino Acids
- Antibody Formation
- Antigen-Antibody Reactions
- Antigens, Plant
- Binding Sites, Antibody
- Humans
- Mutagenesis
- Mutation
- Plant Proteins
- Pollen
- Protein Structure, Tertiary
- Recombinant Proteins