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Article

Sequence conservation predicts T cell reactivity against ragweed allergens

30 Jun 2016

Abstract excerpt

BACKGROUND: Ragweed is a major cause of seasonal allergy, affecting millions of people worldwide. Several allergens have been defined based on IgE reactivity, but their relative immunogenicity in terms of T cell responses has not been studied. OBJECTIVE: We comprehensively characterized T cell responses from atopic, ragweed-allergic subjects to Amb a 1, Amb a 3, Amb a 4, Amb a 5, Amb a 6, Amb a 8, Amb a 9, Amb a...

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PMID: 27359111
DOI: 10.1111/cea.12772

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