Article
Engineered Alt a 13 fragment of Alternaria alternata abrogated IgE binding without affecting T-cell stimulation.
Journal of clinical immunology - 1 Jan 2009
Shankar Jay, Singh Bhanu P, Gaur Shailendra N, Arora Naveen
Abstract excerpt
RATIONALE: Epitopes were delineated for allergenic proteins, but studies are required to identify residues mediating IgE binding. In the present study, the in silico approach was used to identify IgE-binding residues of Alt a 13(1-50) fragment and confirmed by experimental approach. METHOD AND RE...
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