Article
Suppressors of position-effect variegation in Drosophila melanogaster affect expression of the heterochromatic gene light in the absence of a chromosome rearrangement.
Genome - 1 Aug 1998
Clegg N J, Honda B M, Whitehead I P, Grigliatti T A, Wakimoto B, Brock H W, Lloyd V K, Sinclair D A
Abstract excerpt
Suppressors of position-effect variegation (Su(var)s) in Drosophila melanogaster are usually studied in the presence of chromosomal rearrangements, which exhibit variegated expression of euchromatic genes moved near to, or heterochromatic genes moved away from, centromeric heterochromatin. However, the effects of Su(var) mutations on heterochromatic gene expression in the absence of a variegating re-arrangement...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.