Targeted gene correction: a new strategy for molecular medicine.

doi:10.1016/s1357-4310(98)01344-6

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Article

Targeted gene correction: a new strategy for molecular medicine.

Molecular medicine today - 1 Oct 1998

Ye S, Cole-Strauss A C, Frank B, Kmiec E B

Abstract excerpt

Advances, over the past 20 years, in the genetic manipulation of mammalian cells form the scientific basis of gene therapy. A number of strategies are presently being used to replace or augment a dysfunctional gene with a correct copy of itself. Now, a novel approach to correct the dysfunctional...

Topics

Animals
Gene Targeting
Gene Transfer Techniques
Genetic Therapy
Humans
Oligonucleotides
Phenotype

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