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Article

Cytodifferentiating agents affect the replication of herpes simplex virus type 1 in the absence of functional VP16.

Virology - 30 Sept 1998

Preston C M, McFarlane M

Abstract excerpt

The herpes simplex virus type 1 (HSV-1) mutant in1814 encodes an altered form of the virion protein VP16 that is unable to transactivate immediate-early (IE) transcription. As a consequence of the mutation, in1814 initiates productive replication inefficiently after infection of tissue culture cells. Previous studies showed that this defect could be overcome by the inclusion in the culture medium of hexamethylene...

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Source

Identifiers

PMID: 9791032
DOI: 10.1006/viro.1998.9314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cytodifferentiating agents affect the replication of herpes simplex virus type 1 in the absence of functional VP16.PMID 9791032Read ↗

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