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Article

Comparison of methods for identifying transcription units and transcription map of the Werner syndrome gene region.

Genomics - 15 Sept 1998

Hisama F M, Oshima J, Yu C E, Fu Y H, Mulligan J, Weissman S M, Schellenberg G D

Abstract excerpt

To isolate a human disease gene by positional cloning, a critical step is the identification of candidate genes from a targeted genomic region. We used cDNA selection, exon trapping, and genomic sequencing to identify 12 transcription units from a 1.4-Mb genomic region containing the Werner syndrome gene (WRN). This included sequencing of 650 kb in the region of the WRN gene, to date, the most DNA sequenced as...

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Source

Identifiers

PMID: 9790753
DOI: 10.1006/geno.1998.5475

Genes

WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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