Article
Oligomers of the Cdc7/Dbf4 protein kinase exist in the yeast cell.
Molecular & general genetics : MGG - 1 Sept 1998
Shellman Y G, Schauer I E, Oshiro G, Dohrmann P, Sclafani R A
Abstract excerpt
Cdc7/Dbf4 protein kinase is required for the initiation of DNA replication in Saccharomyces cerevisiae. Cdc7/Dbf4 protein kinase is not a cyclin-dependent kinase (CDK), but is regulated in a similar fashion in that the Cdc7 kinase subunit is inactive in the absence of the regulatory subunit Dbf4. In contrast to what is known about CDKs, Cdc7/Dbf4 protein kinase is shown to be an oligomer in the cell in this...
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