Article
Molecular genetic probing of energy coupling by the yeast plasma membrane proton pump.
Acta physiologica Scandinavica. Supplementum - 1 Aug 1998
Soteropoulos P, Wang G, Perlin D S
Abstract excerpt
Genetic probing of PMA1, which encodes the plasma membrane H(+)-ATPase, has highlighted the putative role of the N-terminal half of the enzyme in the coupling process. Recent second-site suppressor studies indicate that significant interactions occur between the region near the site of phosphorylation, stalk segment 3 (S3), and the N-terminal transmembrane segments. Saturation mutagenesis was used to explore I183...
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