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Article

Protein ligand migration mapped by nonequilibrium 2D-IR exchange spectroscopy.

Proceedings of the National Academy of Sciences of the United States of America - 4 Sept 2007

Bredenbeck Jens, Helbing Jan, Nienhaus Karin, Nienhaus G Ulrich, Hamm Peter

Abstract excerpt

2D-IR exchange spectroscopy has been introduced recently to map chemical exchange networks in equilibrium with subpicosecond time resolution. Here, we demonstrate the generalization of 2D-IR exchange spectroscopy to nonequilibrium systems and its application to map light-triggered migration of ligands between different sites in a protein. Within picoseconds after a photodissociating laser pulse, carbon monoxide...

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Identifiers

PMID: 17261808
DOI: 10.1073/pnas.0607758104
PMCID: PMC1964829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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