Article
Ligand migration and protein fluctuations in myoglobin mutant L29W.
Biochemistry - 5 Apr 2005
Nienhaus Karin, Ostermann Andreas, Nienhaus G Ulrich, Parak Fritz G, Schmidt Marius
Abstract excerpt
We have determined eight X-ray structures of myoglobin mutant L29W at various experimental conditions. In addition, infrared spectroscopic experiments are presented, which are discussed in the light of the X-ray structures. Two distinct conformations of the CO-ligated protein were identified, giving rise to two stretching bands of heme-bound CO. If L29W MbCO crystals are illuminated around 180 K, a deoxy species...
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