Article
Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 1998
Kostetskii I, Yuan S Y, Kostetskaia E, Linask K K, Blanchet S, Seleiro E, Michaille J J, Brickell P, Zile M
Abstract excerpt
Vitamin A requirement for early embryonic development is clearly evident in the gross cardiovascular and central nervous system abnormalities and an early death of the vitamin A-deficient quail embryo. This retinoid knockout model system was used to examine the biological activity of various natu...
Topics
- Animals
- Cardiovascular System
- Gene Expression Regulation, Developmental
- In Situ Hybridization
- Phenotype
- Quail
- RNA, Messenger
- Receptors, Retinoic Acid
- Retinoic Acid Receptor alpha
- Retinoid X Receptors
- Retinoids
- Time Factors
- Transcription Factors
