Article
Distinct roles for hindbrain and paraxial mesoderm in the induction and patterning of the inner ear revealed by a study of vitamin-A-deficient quail.
Developmental biology - 1 Sept 2005
Kil Sung-Hee, Streit Andrea, Brown Stephen T, Agrawal Nidhi, Collazo Andres, Zile Maija H, Groves Andrew K
Abstract excerpt
The hindbrain and cranial paraxial mesoderm have been implicated in the induction and patterning of the inner ear, but the precise role of the two tissues in these processes is still not clear. We have addressed these questions using the vitamin-A-deficient (VAD) quail model, in which VAD embryos lack the posterior half of the hindbrain that normally lies next to the inner ear. Using a battery of molecular...
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