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Article

Retinoic acid is a negative physiological regulator of N-cadherin during early avian heart morphogenesis.

Development, growth & differentiation - 1 Dec 2009

Romeih Mahmoud, Cakstina Inese, Zile Maija H

Abstract excerpt

The vitamin A-deficient (VAD) early avian embryo has a grossly abnormal cardiovascular system that is rescued by treating the embryo with the vitamin A-active form, retinoic acid (RA). Here we examine the role of N-cadherin (N-cad) in RA-regulated early cardiovascular morphogenesis. N-cad mRNA and protein are expressed globally in the presomite through HH14 normal and VAD quail embryos. The expression in VAD...

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PMID: 19843154
DOI: 10.1111/j.1440-169X.2009.01134.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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