Negative strand RNA synthesis by temperature-sensitive mutants of mouse hepatitis virus.

doi:10.1007/978-1-4615-5331-1_27

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Article

Negative strand RNA synthesis by temperature-sensitive mutants of mouse hepatitis virus.

Advances in experimental medicine and biology - 1 Jan 1998

Younker D R, Sawicki S G

Abstract excerpt

Mutants of the A59 strain of mouse hepatitis virus (MHV) were studied to determine the effects of temperature shift on negative and positive strand RNA synthesis. Mutant LA 9 was originally reported to have a selective temperature sensitive defect in negative strand synthesis. We found that this...

Topics

Animals
Mice
Murine hepatitis virus
Mutation
RNA, Viral
Temperature

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