Article
Variable distribution of TFF2 (Spasmolysin) alleles in Europeans does not indicate predisposition to gastric cancer.
Human heredity - 1 Jan 1999
dos Santos Silva E, Kayademir T, Regateiro F, Machado J C, Savas S, Dobosz T, Blin N, Gött P
Abstract excerpt
Peptides belonging to the trefoil factor family (TFF) protect the gastrointestinal epithelia. Overexpression of TFFs was observed in pathological conditions such as gastritis, ulceration, metaplasia and neoplasia of the gastrointestinal tract. The aims of this work were to investigate the recently described TFF2 gene polymorphism in different European populations. DNA samples from blood of healthy individuals and...
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