Analysis of genes within the HLA region affecting susceptibility to ulcerative colitis.

doi:10.1016/0198-8859(93)90113-f

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Article

Analysis of genes within the HLA region affecting susceptibility to ulcerative colitis.

Human immunology - 1 Feb 1993

Sugimura K, Asakura H, Mizuki N, Inoue M, Hibi T, Yagita A, Tsuji K, Inoko H

Abstract excerpt

To clarify the molecular relationship between HLA loci and ulcerative colitis (UC) in Japanese patients, we performed HLA-DP genotyping by the PCR-RFLP method and studied tumor necrosis factor beta-chain genetic polymorphism by Southern hybridization, in addition to conventional serologic typing....

Topics

Adult
Amino Acid Sequence
Colitis, Ulcerative
Disease Susceptibility
Female
Genes, MHC Class I
Genes, MHC Class II
Genetic Linkage
Genotype
HLA Antigens
Histocompatibility Testing
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphotoxin-alpha

Male

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 8096500
DOI: 10.1016/0198-8859(93)90113-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8096500-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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