Article
A tailless Drosophila lamin Dm0 fragment reveals lateral associations of dimers.
Journal of structural biology - 1 Sept 1998
Sasse B, Aebi U, Stuurman N
Abstract excerpt
An early step in nuclear lamin polymerization is the longitudinal, head-to-tail association of lamin dimers through the highly conserved end segments of their rod domains. Lamin fragments lacking the carboxy-terminal tail domain (tailless lamins) form long, thin protofilaments more readily than f...
Topics
- Animals
- Dimerization
- Drosophila
- Drosophila Proteins
- Immunoglobulin Fab Fragments
- Intermediate Filaments
- Lamins
- Microscopy, Electron
- Models, Molecular
- Mutation
- Nuclear Proteins
- Particle Size
- Peptide Fragments
- Protein Binding
- Protein Conformation
- Recombinant Proteins
- Ultracentrifugation