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Article

Novel polymorphism in the promoter region of the human nerve growth-factor gene.

International journal of immunogenetics - 1 Dec 2005

Alam M, Pravica V, Fryer A A, Hawkins C P, Hutchinson I V

Abstract excerpt

We describe a novel T to C transition at position -198 from the transcription start of the human nerve growth-factor (NGF) gene. In British Caucasoid healthy control group that we have genotyped, T and C allele frequencies are 0.633 and 0.367, respectively. This polymorphism affects vitamin D receptor (VDR) binding to its motif in the NGF promoter.

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Source

Identifiers

PMID: 16313302
DOI: 10.1111/j.1744-313X.2005.00541.x

Genes

NGF
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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