Article
In vitro propagated dendritic cells from patients with human-papilloma virus-associated preneoplastic lesions of the uterine cervix: use of Flt3 ligand.
Cancer immunology, immunotherapy : CII - 1 Oct 1998
Hubert P, Greimers R, Franzen-Detrooz E, Doyen J, Delanaye P, Boniver J, Delvenne P
Abstract excerpt
Dendritic cells (DC) are the most efficient antigen presenting cells. The clinical use of DC as vectors for antitumor and anti-infectious disease immunotherapy has been limited by their low level and accessibility in normal tissue. Substantial numbers of DC can be generated from peripheral blood...
Topics
- Adult
- Carcinoma, Squamous Cell
- Cell Division
- Dendritic Cells
- Female
- Humans
- Leukocytes, Mononuclear
- Membrane Proteins
- Papillomaviridae
- Phenotype
- Precancerous Conditions
- Tumor Cells, Cultured
- Uterine Cervical Neoplasms