Article
Mutations in the carboxy terminus of the beta and gamma subunits of the epithelial sodium channel are not present in patients with hypertensive crisis.
European journal of clinical investigation - 1 Sept 1998
Födinger M, Hirschl M M, Schedler D, Herkner H, Bur A, Laggner A N, Hörl W H, Sunder-Plassmann G
Abstract excerpt
BACKGROUND: The pathophysiology of hypertensive crises is poorly understood. To date, no information is available about genetic determinants underlying the individual risk for development of hypertensive urgencies or emergencies. Recently, mutations in the beta subunit (h beta ENaC) and the gamma...
Topics
- Adult
- Aged
- Aldosterone
- Amino Acid Sequence
- Base Sequence
- DNA
- Emergencies
- Female
- Humans
- Hypertension
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Potassium
- Protein Conformation
- Renin