Article
Mutations in the carboxy terminus of the beta and gamma subunits of the epithelial sodium channel are not present in patients with hypertensive crisis.
European journal of clinical investigation - 1 Sept 1998
Födinger M, Hirschl M M, Schedler D, Herkner H, Bur A, Laggner A N, Hörl W H, Sunder-Plassmann G
Abstract excerpt
BACKGROUND: The pathophysiology of hypertensive crises is poorly understood. To date, no information is available about genetic determinants underlying the individual risk for development of hypertensive urgencies or emergencies. Recently, mutations in the beta subunit (h beta ENaC) and the gamma subunit (h gamma ENaC) of the human epithelial sodium channel (hENaC) have been shown to result in excessive elevation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.