Article
Polymorphisms of the gamma subunit of the epithelial Na+ channel in essential hypertension.
Journal of hypertension - 1 May 1999
Persu A, Coscoy S, Houot A M, Corvol P, Barbry P, Jeunemaitre X
Abstract excerpt
OBJECTIVE: The gamma subunit of the epithelial Na channel (gammaENaC) has been implicated in Liddle's syndrome. The objective of this study was to examine its status in essential hypertension. DESIGN AND METHODS: The search for molecular variants was performed using the SSCP technique after determination of the intron-exon boundaries of the transcribed sequence. We found an additional 205 bp intron splitting the...
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