Article
Genetic screening of SCNN1B and SCNN1G genes in early-onset hypertensive patients helps to identify Liddle syndrome.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2018
Yang Kun-Qi, Lu Chao-Xia, Fan Peng, Zhang Ying, Meng Xu, Dong Xue-Qi, Luo Fang, Liu Ya-Xin, Zhang Hui-Min, Wu Hai-Ying, Cai Jun, Zhang Xue, Zhou Xian-Liang
Abstract excerpt
BACKGROUND: Liddle syndrome is an autosomal dominant form of monogenic hypertension. Phenotypic variability makes it difficult to identify patients with Liddle syndrome, resulting in misdiagnosis and severe complications at early age. OBJECTIVES: To identify mutation in SCNN1B and SCNN1G genes in an adolescent with suspicious Liddle syndrome and his family members and to explore the screening target subjects of...
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