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Article

Genetic analysis of the epithelial sodium channel in Liddleʼs syndrome

1 Aug 1998

Abstract excerpt

BACKGROUND: Liddle's syndrome is an autosomal inheritable disorder that causes hypertension due to excess function of sodium channel. OBJECTIVE: To analyze the DNA sequence of the amiloride-sensitive epithelial sodium channel (ENaC) in three patients who had low-renin hypertension with hypokalemia. The patients included a 24-year-old woman and her 20-year-old brother whose mother was hypertensive. The third...

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PMID: 9794716
DOI: 10.1097/00004872-199816080-00008

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