Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A constitutively activated mutant of galphaq down-regulates EP-cadherin expression and decreases adhesion between ectodermal cells at gastrulation.

Mechanisms of development - 1 Aug 1998

Rizzoti K, Paquereau L, Shaw A, Knibiehler B, Audigier Y

Abstract excerpt

We have examined the expression and function of the heterotrimeric GTP-binding protein Gq during early Xenopus embryogenesis. Abundant XGalphaq transcripts were detected in oocytes and early embryos by Northern blot analysis. In situ hybridization revealed that these transcripts are confined to the animal hemisphere of the mature oocyte and to the presumptive ectoderm of cleaving embryos. Microinjection at the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to Gene Expression Regulation, Developmental

Share to GTP-Binding Proteins

Share to Mutation

Share to Phenotype

Share to RNA, Messenger

Source

Identifiers

PMID: 9767085
DOI: 10.1016/s0925-4773(98)00106-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

A constitutively activated mutant of galphaq down-regulates EP-cadherin expression and decreases adhesion between ectodermal cells at gastrulation.PMID 9767085Read ↗

Co-operation of Gsalpha and Gbetagamma in maintaining G2 arrest in Xenopus oocytes.Semantic proximity Read ↗

Anterior structural defects by misexpression of Xgbx-2 in early Xenopus embryos are associated with altered expression of cell adhesion molecules.Semantic proximity Read ↗

Altered levels of Gq activity modulate axonal pathfinding in Drosophila.Semantic proximity Read ↗

Localization of two IQGAPs in cultured cells and early embryos of <i>Xenopus laevis</i>Semantic proximity Read ↗

Maternal beta-catenin and E-cadherin in mouse development.Semantic proximity Read ↗

Myocyte enhancer factors-2B and -2C are required for adhesion related kinase repression of neuronal gonadotropin releasing hormone gene expression.Semantic proximity Read ↗

Posterior localization of the Drosophila Gi alpha protein during early embryogenesis requires a subset of the posterior group genes.Semantic proximity Read ↗

Dominant negative expression of a cytoplasmically deleted mutant of XB/U-cadherin disturbs mesoderm migration during gastrulation in Xenopus laevis.Semantic proximity Read ↗

EphA4 catalytic activity causes inhibition of RhoA GTPase in Xenopus laevis embryos.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.