Article
Vitamin D receptor alleles and rates of bone loss: influences of years since menopause and calcium intake.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 1995
Krall E A, Parry P, Lichter J B, Dawson-Hughes B
Abstract excerpt
A genetic marker for the 1,25-dihydroxyvitamin D receptor (VDR) is reported to account for much of the heritable component of bone density. It is not known whether VDR genotype influences bone accretion or loss, or how it is related to calcium metabolism. The VDR genotype was determined in 229 he...
Topics
- Absorptiometry, Photon
- Aged
- Aging
- Alleles
- Base Sequence
- Bone Density
- Calcium, Dietary
- Cohort Studies
- DNA Primers
- Female
- Femur Neck
- Genotype
- Humans
- Longitudinal Studies
- Lumbar Vertebrae
- Middle Aged
- Molecular Sequence Data
- Osteoporosis, Postmenopausal
