Article
Myofibroblast transformation of cat corneal endothelium by transforming growth factor-beta1, -beta2, and -beta3.
Investigative ophthalmology & visual science - 1 Oct 1998
Petroll W M, Jester J V, Bean J J, Cavanagh H D
Abstract excerpt
PURPOSE: Under certain pathophysiologic conditions, the corneal endothelium can produce an abnormal posterior collagenous layer (PCL) that reduces light transmission. Previous studies suggest that formation of PCLs can result from transformation of endothelial cells to a proliferative myofibroblast phenotype. The purpose of this study was to determine the potential role of transforming growth factor (TGF)-beta on...
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