Article
Myofibroblast transformation of cat corneal endothelium by transforming growth factor-beta1, -beta2, and -beta3.
Investigative ophthalmology & visual science - 1 Oct 1998
Petroll W M, Jester J V, Bean J J, Cavanagh H D
Abstract excerpt
PURPOSE: Under certain pathophysiologic conditions, the corneal endothelium can produce an abnormal posterior collagenous layer (PCL) that reduces light transmission. Previous studies suggest that formation of PCLs can result from transformation of endothelial cells to a proliferative myofibrobla...
Topics
- Animals
- Cats
- Cell Count
- Cell Differentiation
- Cell Division
- Endothelium, Corneal
- Extracellular Matrix Proteins
- Fibroblasts
- Ki-67 Antigen
- Membrane Proteins
- Microscopy, Confocal
- Organ Culture Techniques
- Phalloidine
- Phenotype
- Phosphoproteins
- Transforming Growth Factor beta
- Zonula Occludens-1 Protein