Article
Extensive polymorphism of the FUT2 gene in an African (Xhosa) population of South Africa.
Human genetics - 1 Aug 1998
Liu Y, Koda Y, Soejima M, Pang H, Schlaphoff T, du Toit E D, Kimura H
Abstract excerpt
The human secretor type alpha(1,2)fucosyltransferase gene (FUT2) polymorphism was investigated in Xhosa and Caucasian populations of South Africa by polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing. Six new base substitutions were found in the coding region of FUT2. A single base (C) deletion at nucleotide 778, which led to a frame shift and produced a stop codon at codon 275,...
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