Article
Denaturing high-performance liquid chromatography-based genotyping and genetic variation of FUT2 in Sri Lanka.
Transfusion - 1 Dec 2005
Soejima Mikiko, Koda Yoshiro
Abstract excerpt
BACKGROUND: Human ABO-secretor locus (FUT2) is highly polymorphic in many human populations. STUDY DESIGN AND METHODS: The applicability of denaturing high-performance liquid chromatography (DHPLC) analysis was evaluated for genotyping the FUT2 in two Sri Lankan populations (Tamil and Sinhalese). RESULTS: Although DHPLC failed to detect one allele, 302C>T, of eight alleles, this method reduces the number of...
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