Article
Genetic variation of FUT2 in a Vietnamese population: identification of two novel Se enzyme-inactivating mutations.
Transfusion - 1 Jun 2012
Soejima Mikiko, Fujimoto Ryo, Agusa Tetsuro, Iwata Hisato, Fujihara Junko, Takeshita Haruo, Minh Tu Binh, Trang Pham Thi Kim, Viet Pham Hung, Nakajima Tamiko, Yoshimoto Joji, Tanabe Shinsuke, Koda Yoshiro
Abstract excerpt
BACKGROUND: The human FUT2 gene encodes a secretor-type α(1,2)fucosyltransferase, and many population-specific polymorphisms have been reported in the coding region. STUDY DESIGN AND METHODS: Direct sequencing, real-time polymerase chain reaction, and high-resolution melt (HRM) analysis were done to detect single-nucleotide polymorphism (SNPs) and copy number variations (CNVs) in a Vietnamese population. The...
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