Article
Five novel missense mutations of the Lewis gene (FUT3) in African (Xhosa) and Caucasian populations in South Africa.
Human genetics - 1 Jun 1998
Pang H, Liu Y, Koda Y, Soejima M, Jia J, Schlaphoff T, Du Toit E D, Kimura H
Abstract excerpt
Five novel missense mutations, viz., C304 A, T370 G, G484 A, G667 A, and G808 A, in the Lewis gene (FUT3) were detected in African (Xhosa) and Caucasian individuals in South Africa. These single base substitutions may result in changes in amino acid residues from Gln102 to Lys in the 304 mutation...
Topics
- Alleles
- Animals
- Asian People
- Black People
- COS Cells
- Fucosyltransferases
- Gene Expression
- Gene Frequency
- Genotype
- Haplotypes
- Humans
- Mutation
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- South Africa
- Transfection
- White People