Article
Systematic sequence analysis of the human fucosyltransferase 2 (FUT2) gene identifies novel sequence variations and alleles.
Transfusion - 1 Aug 2007
Yip Shea Ping, Lai Siu Kin, Wong Maria L
Abstract excerpt
BACKGROUND: The FUT2 gene regulates the expression of ABH antigens in body secretions and hence controls the secretor status. It is highly polymorphic. STUDY DESIGN AND METHODS: Healthy Chinese (n = 79) and Caucasian (n = 20) subjects were recruited for this study. Lewis blood group and secretor status were determined. The entire FUT2 coding region was amplified and screened for sequence variations by...
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