Multiple phenotype modeling in gene-mapping studies of quantitative traits: power advantages.

Abstract excerpt

Genomewide searches for loci influencing complex human traits and diseases such as diabetes, hypertension, and obesity are often plagued by low power and interpretive difficulties. Attempts to remedy these difficulties have typically relied on, and have promoted the use of, novel subject-ascertai...

Topics

• Chromosome Mapping
• Genetic Linkage
• Humans
• Models, Genetic
• Models, Statistical
• Multifactorial Inheritance
• Multivariate Analysis
• Phenotype
• Quantitative Trait, Heritable
• Reproducibility of Results