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Article

Screening male intracytoplasmic sperm injection candidates for mutations of the follicle stimulating hormone receptor gene.

Human reproduction (Oxford, England) - 1 Aug 1998

Tuerlings J H, Ligtenberg M J, Kremer J A, Siers M, Meuleman E J, Braat D D, Hoefsloot L H, Merkus H M, Brunner H G

Abstract excerpt

Follicle stimulating hormone (FSH) is considered to be essential for spermatogenesis. Therefore, genetic abnormalities of FSH signalling on testicular Sertoli cells would be expected to affect sperm production negatively in males. Inactivating FSH receptor mutations have been reported earlier in...

Topics

Cytoplasm
Fertilization in Vitro
Follicle Stimulating Hormone
Humans
Infertility, Male
Male
Microinjections
Mutation
Oligospermia
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, FSH

Spermatozoa

Source

Identifiers

PMID: 9756276
DOI: 10.1093/humrep/13.8.2098

Genes

OAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9756276-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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