Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis.

doi:10.1016/s0016-5085(98)70265-3

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Article

Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis.

Gastroenterology - 1 Oct 1998

Guyader D, Jacquelinet C, Moirand R, Turlin B, Mendler M H, Chaperon J, David V, Brissot P, Adams P, Deugnier Y

Abstract excerpt

BACKGROUND & AIMS: The diagnosis of hemochromatosis is now possible for C282Y homozygous patients using noninvasive molecular genetic tests. The aim of this study was to define noninvasive factors predictive of severe fibrosis (bridging fibrosis or cirrhosis) to avoid unnecessary liver biopsies i...

Topics

Adult
Evaluation Studies as Topic
Female
Hemochromatosis
Homozygote
Humans
Liver Cirrhosis
Male
Middle Aged
Models, Theoretical
Multivariate Analysis
Mutation
Prognosis

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