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Article

Penetrance of the C28Y/C282Y genotype of the HFE gene.

Scandinavian journal of gastroenterology - 1 Sept 2007

Asberg Arne, Hveem Kristian, Kannelønning Kjell, Irgens Wenche Øiestad

Abstract excerpt

OBJECTIVE: Hereditary hemochromatosis is a common genetic disease caused by accumulation of iron in the body. Most cases are homozygous for the C282Y mutation in the HFE gene, but only a minority of homozygotes will ever suffer from clinical hemochromatosis. Estimates of the penetrance of the C282Y/C282Y genotype vary greatly. The purpose of this study was to estimate the penetrance using a stringent definition,...

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Source

Identifiers

PMID: 17710673
DOI: 10.1080/00365520701245488

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Penetrance of the C28Y/C282Y genotype of the HFE gene.PMID 17710673Read ↗

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